An Alternative Treatment for HIV/AIDS: Gallium Nitrate to Prevent HIV Infection and AIDS in Anal Sex

By George Eby
Austin, Texas
george.eby@george-eby-research.com
August 2, 2015

Below is a National Institute of Health (NIH) meeting abstract of results obtained using gallium nitrate to inhibit HIV-1 replication in vitro. As you read this abstract, consider that gallium nitrate might be a useful anti-HIV agent for preventing and treating HIV infection and saving lives. This material is for education purposes only, and it is not a "proven" preventative or cure for HIV/AIDS. Condoms are always recommended, but too many people go bareback, thus this treatment/preventative may be life-saving to them.



Gallium Nitrate: a Potent Inhibitor of HIV-1 Infection In Vitro

STAPLETON JT, KLINZMAN D, OLAKANMI O, WUENSCHMANN S, SCHLESINGER LS, BRITIGAN BE; Interscience Conference on Antimicrobial Agents and Chemotherapy. Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 1999 Sep 26-29; 39: 319 (abstract no. 934).

Univ. of Iowa and Iowa City VA Med. Ctr., Iowa City, IA.

BACKGROUND: Gallium nitrate (Ga) is a potent ribonucleotide reductase inhibitor which was previously shown to inhibit avian retroviruses. Although the mechanism of its anti-retroviral activity was not elucidated, it is known that Ga inhibits cellular activation in a manner analogous to hydroxyurea (HU). Since Ga is administered to humans intravenously, and oral preparations are being developed, we evaluated Ga for its anti-HIV activity, and compared it with HU. METHODS: Various concentrations of Ga or HU were added to 1 x 106 PHA/IL2 stimulated PBMC's 24 hours prior to infection with HIV-1 stock virus. 16 hrs. following infection, cells were washed and culture supernatants were obtained 4 and 7 days post-infection. HIV p24 antigen production in culture supernatants was determined by ELISA. To determine if RT inhibitors were potentiated by Ga, zidovudine(zdv), ddI and ddC were also evaluated with and without Ga. RESULTS: Ga reproducibly inhibited HIV replication at concentrations which did not inhibit cellular proliferation or viability. Ga IC50 ranged from 4 to 10 micromolar, which was approximately 15-fold lower than HU (120 micromolar) in our culture system. Using sub-inhibitory concentrations of zdv, ddI and ddC, Ga potentiated the inhibitory effects of these nucleoside analogs. The addition of transferrin to the cell culture did not appear to have a significant effect on the antiviral activity of Ga. CONCLUSIONS: Ga was considerably more potent than HU in inhibiting HIV-1 replication in stimulated PBMC culture. This effect potentiated the effect of anti-HIV nucleoside RT inhibitors. Ga inhibits the same cellular target as HU although it does so by a different mechanism of action. Since the inhibitory concentration of Ga is achievable in humans, and the relative potency of Ga is greater than HU, additional studies of Ga appear warranted. Blood levels of gallium need to reach 0.10 millimolar (100 micromolar) to be inhibitory, which is a measurement that medical laboratory clinics could determine through blood tests.

The above National Libray of Medicine NIH abstract is located here: Gallium Nitrate: a Potent Inhibitor of HIV-1 Infection In Vitro.



alternative treatment for HIV/AIDS - gallium nitrateGallium nitrate terminates HIV replication and restores T-cell immune system according to Stapleton! INTERESTING! I noticed that Stapleton had filed a patent on his discovery, and it is located here. Perhaps the most important point made in his patent is shown in this figure. Gallium(III) inhibits HIV-1 replication, especially when its concentration is 100 micromolar or more, a concentration readily obtained in blood and other body fluids. Others have filed similar patents, like this one by Bernstein. They each say that gallium(III) inhibits HIV-1 replication. Additionally, gallium nitrate potentiates the effects of NRTIs such as didexoyinosine, dideoxycytidine and azidothymidine. What is gallium? It is an element immediately to the right of zinc on the period table of the elements. It is a mineral, like zinc but different.

A CASE REPORT OF GALLIUM NITRATE FOR HIV: A male HIV positive client who was treating his arthritis with gallium nitrate, told me in February of 2009 that before taking gallium that his CD4+ T-cell count was very low at < 200 cells/mm3. After taking gallium nitrate his CD4+ T-cell lymphocyte count rose to 2200, more than an 11-fold increase. This is consistent with the finding of Stapleton that gallium nitrate prevented T-cell death.

Had my client (who was treating his horse with my navicular disease gallium nitrate product and his own arthritis) not told me this, I would never have looked into this material. I have learned a lot since then, and would like to share it with you. Perhaps you will see why I strongly believe that gallium nitrate will be shown to be an outstanding alternative treatment for HIV/AIDS. Notice from Stapleton's figure that gallium nitrate eliminated HIV at concentrations over 100 micromolar. It restored my client's T-cell immunity, just like Stapleton reported it would do in his patent. Isn't that the goal of HIV/AIDS treatments? Kill HIV and restore T-cell immunity? What I found out centers on anal sex, mainly men having sex with men (MSM), as the main means of transmitting HIV in the United States. Consequently, I have focused mainly on anal sex in this essay, and am particularly concerned about anal sex as result of "the heat of the moment". Use of gallium nitrate orally and topically after anal sex may, therefore, be particularly rewarding.

Man fucking man

ANAL SEX - TABOOS vs. PLEASURE vs. RISK: From antiquity to now there have been, and are now, various taboos, both secular, moral, legal and religious, that range from discouraging anal sex to laws prohibiting it (even between married couples) and even religious views that proclaim the participants will rot in hell. I suspect U.S. President Barack Obama is the first national leader to support anal sex, through his support for same sex marriage. Also, Pope Francis said the church has the right to express its opinions but not to "interfere spiritually" in the lives of gays and lesbians, expanding on explosive comments he made in July about not judging homosexuals. Perhaps this will eventually end the Catholic Church's opposition to safe sex education in schools and its demonization of sex, condoms and AIDS.

Men have explored anal sex and found varying satisfaction with it, with views ranging from total disdain to it, to anal sex being the absolute ultimate in sexual pleasure. Women have the same feeling and often use anal sex as a substitute for vaginal sex during their fertile period and menses. Transgender women enjoy anal sex, since their anus is, essentially, their "vagina" until they get their sex change surgery.

The anus has a high concentration of nerve endings and is an erogenous zone. This makes anal sex pleasurable for both the insertive partner and the receptive partner. In addition to nerve endings, pleasure from anal intercourse occurs due to the shared wall between the anus and the prostate for males, often resulting in erections and ejaculation. Prostate massage using fingers, dildos, or other toys typically produces excitation. Females usually need clitoral finger stimulation in addition in order to climax. For a male insertive partner, the tightness of the anus can be a source of pleasure via the tactile pressure on the penis. This pressure can be much higher in men than women, since men have smaller pelvic openings than women.

Here is a link to a good anal sex "how-to-do-it" site. It is based upon the book on anal sex titled "Anal Pleasure and Health: A Guide for Men Women and Couples" by Jack Morin PhD. His book is considered by many to be the best book on the subject. Accordingly, the discussion of anal sex in this essay, particularly the details of the subject, follow his book.

Perhaps the old taboos and disdain for anal sex result from the observation that the only God-given role of the anus is to expel feces and gas. Feces is a waste product of all living creatures and is nearly always held in disdain. Perhaps these views about feces extend to the anus. Anal sex has been practiced for as long as there were people and it is practiced world-wide in all cultures and nations, whether the leaders of those cultures, secular, political or religious, condemn it or not. Anal sex is practiced by both men and women of all ages, whether they be heterosexual, bisexual or homosexual.

If you think that anal sex is just for gay men, see this Center for Disease Control research report that shows that: "Among adults 25–44 years of age, 40 percent of men and 35 percent of women have had anal sex with an opposite-sex partner, and about 6.5 percent of men 25–44 years of age (90% of gays) have had anal sex with another man." Since women have strongly endorsed anal sex, it is here to stay and we need to consider the risks, as well as the rewards.

Anal sex is a very high-risk behavior for the infection of HIV and many other STDs including chlamydia, gonorrhea, hepatitis A, B and C, herpes and human papillomavirus. This essay only considers the risks of the Human Immunodeficiency Virus (HIV) infection, which is a permanent, life-long infection of the blood, other bodily fluids including semen, pre-cum, breast milk, vaginal fluids, anal mucous, and human genetics. Other body fluids and waste products—like feces, nasal fluid, saliva, sweat, tears, urine, or vomit—don’t contain enough HIV to be infectious, unless they have blood mixed in them and you have significant and direct contact with them. Anal sex is the most likely sexual way to contract HIV infection, which leads to Acquired Immune Deficiency Syndrome (AIDS) which is eventually fatal, either by the disease or suicide.

IMPACT OF HIV/AIDS: What I do know is that people get acquired immune deficiency syndrome (AIDS) from the human immunodeficiency virus (HIV) and die within a few years of opportunistic infections from having an impaired CD-4 T-cell lymphocyte immune system and other immune system dysfunctions without treatment. The main cellular targets of HIV-1 are the CD4+ T-helper/inducer subset of lymphocytes, CD4+ cells of macrophage lineage and dendritic cells. HIV gets into cellular genetics, and becomes a permanent infection. The most prominent effect of HIV is its T-helper lymphocyte cell suppression and lysis effects. The CD-4 T-cell lymphocytes (thymus derived) are simply killed off or deranged to the point of being non-functional (they do not respond to foreign antigens). The destruction of CD-4 T-cells in the intestinal tract is far greater than in the peripheral blood. Since these cells orchestrate the entire immune system response to pathogens, we cannot live without them for long. The infected B-cell lymphocytes (bone marrow derived) cannot produce enough antibodies either. Thus the immune system collapses leading to the familiar AIDS complications. HAART does not restore CD4+ cells in the intestinal tract, even though it does in peripheral blood. People living with HIV are 60 times more likely than their peers to get non-Hodgkin lymphoma, a cancer of the white blood cells due to their low CD-4 counts. Interestingly, IV gallium nitrate is being formally tested for this disease. Another disease that is a complication of AIDS is tuberculosis, and gallium nitrate kills the bacteria (Mycobacterium tuberculosis) that cause it. If you want to know more about how HIV works, see this page. HIV can infect anybody, regardless of sex, age, ethnicity or sexual orientation. HIV has a rapid replication cycle. Consequently, gallium nitrate with its ability to very greatly inhibit the replication of HIV makes it an outstanding alternative treatment for HIV/AIDS, especially since it is believed to restore the T-cell lymphocyte system.

A WAKE UP CALL TO MSM: Because of the devastation resulting from HIV/AIDS to the male gay community, it is mainly to MSM that I address this essay. What about gallium nitrate? If it is in the blood before infection occurs, it is likely that it will prevent HIV infection and be an outstanding alternative treatment for HIV/AIDS. This is extremely important considering that HIV will get into DNA if infection occurs and it will be permanent.

MEN WHO HAVE SEX WITH MEN: Men who receive a penis (no condom) in their anus (bottoms) have an HIV prevalence 60-times higher than the general population, accounting for over fifty percent of all HIV diagnoses in the U.S.A. This horrific data results mainly from bareback (no condom) anal intercourse. This is because the anus and rectum (of both men and women) are 18 times more susceptible to infection by HIV infected semen than semen ejaculated into the vagina, and 36 times more susceptible than HIV infected semen ejaculated into the mouth in oral sex. Incidence of unprotected anal sex at least once in the past 12 months increased from 48% in 2005 to 57% in 2011 (p<0.001) according to this Center for disease Control report. Consequently, the risk for contracting HIV has been increasing. GET TESTED FREQUENTLY! You might try the at home test called Oraquick, which is claimed to have used by health care professionals for many years. Here is what the FDA says about the test.

This Center for Disease Control page indicates that oral sex is not a particularly high risk means of transmitting HIV infection. The risk of HIV transmission through oral sex is much less than that from anal or vaginal sex—but it is not zero. Performing oral sex on an HIV-infected man, with ejaculation into the mouth, is the riskiest oral sex activity. Factors that may increase the risk of HIV transmission through oral sex are oral ulcers, bleeding gums, genital sores, and the presence of other sexually transmitted infections. Saliva contains enzymes that break down the virus, and the mucus membranes in the mouth are much more protective than anal or vaginal tissue. However, any break in the mucus membranes of the mouth offers a perfect transmission route for HIV transmission. For HIV transmission to occur, the virus must get into the blood stream. The CDC page also shows the risks of numerous other potential means of transmitting HIV. Blood, semen, pre-ejaculate (pre-cum), vaginal secretions, and breast milk from an HIV-infected person are well known to transmit HIV. Consequently, an alternative treatment for HIV/AIDS would suggest that gallium be in the blood in an effort to insure that infection does not occur.

What has been under-reported, and perhaps unknown to many, is that anal mucus also can transmit HIV. In fact, this report shows that anal mucus carries more HIV than semen or blood from the same subject. Very little research addresses this topic, but a study from the University of Washington, Seattle, found that levels of HIV RNA in anal mucus in gay men were higher than those in blood or semen – by about 500% in the case of blood, and 2500% in the case of semen. As with blood and semen, anal mucus must come in contact with a mucus membrane or damaged tissue for transmission to possibly occur. This can occur through the foreskin and surrounding areas, the eye of the penis to the urethra (also a mucous membrane), and through tiny (often invisible) breaks in the skin of the penis when in contact with HIV-infected anal mucus. Consequently, gallium nitrate in the anus/rectum should be a good alternative treatment for HIV/AIDS.

Recent studies in HIV-1 infected individuals have demonstrated that the gastrointestinal (GI) tract is preferentially and profoundly affected during acute and chronic HIV-1 infection. Four studies provided estimates of the transmission risk for a single act of unprotected receptive anal intercourse. Pooling their data, the summary estimate is 1.4%. For long term multiple exposures between MSM partners, the risk of HIV transmission rose to 40%.

About one-fourth of all MSM in a CDC study was infected with HIV, meaning their semen was also infected. Here is a Reuters article about the extremely high infection rate. Black MSM were twice as likely to have HIV infected semen (about half had HIV) than other MSM. Although MSM account for only about 2% of the U.S. population, they had over 50% of the known cases of HIV infection.

Much of the increased risk of HIV infection from anal penetration results from tiny tears and minor damage to the anus/rectum by the penis resulting in infection of blood. The main risk is HIV infection of the Peyer's patches in the immune system of the intestinal tract, which can be infected by HIV infected blood or semen. Regardless, tops should not be rough with bottoms since anal/rectum injuries very greatly increase the risk of HIV transmission. See bottom of this page for role of gallium nitrate in stopping bleeding. Consequently, the blood should contain enough gallium nitrate to be good alternative treatment for HIV/AIDS.

A CLEAN RECTUM IS A HAPPY RECTUM: Ideally, anal sex should be as natural as possible, meaning no prior douching or artificial anal/rectal cleaning. However, feces should not be encountered in anal sex for several important reasons, usually dictating the necessity for douching before anal sex. Obviously, it is terribly gross and stinky to get feces on one's penis, testicles, legs, behind, other body parts and bedding. Second, feces may contain tiny sharp particles from undigested food, usually nuts, shells (popcorn) and bone. Therefore, feces can be abrasive and can cause tearing, damage to the rectum and anus, cause discomfort during anal sex and greatly increase the risk of HIV transmission. In heat of the moment anal sex, especially in MSM, feces is nearly always encountered, perhaps contributing to the very high incidence of HIV in MSM. Cleaning the anus/rectum is best accomplished simply by squatting - not sitting - to defecate followed by anal/rectal washing using some kind of lightly pressurized water source. A shower bidet is ideal. Use only warm water at a low pressure without any cleaning agents as they can harm the delicate lining of the rectum. Too much pressure can also be harmful. Here is a site on anal douching and anal lubrication. Anal douching does not seem to increase STI risk.

Somewhat outside this discussion, sitting upright on a commode seat rather than squatting to poop can cause a number of serious diseases over a life-time. Squatting helps the bowels move more freely. Yes, butt! I have found that this is an incomplete discovery, and that vastly better pooping can result by leaning and rotating the upper torso. First, lean to the left and rotate, then lean and rotate to forward then lean and rotate to right, then to the rear, then to the left - if necessary. Only go clockwise. Do not rotate counterclockwise. Even hard compacted poop having residence in the bowels for days readily comes out with no pain or discomfort. No unusual exertion is needed to void the bowels if one rotates and leans!

Anal douching with 1% gallium nitrate solutions is very important after anal sex, especially when semen has been ejaculated into the rectum. Removing the majority of semen and pre-cum by douching with an anti-HIV solution (gallium nitrate 1%) will greatly help prevent HIV infection. It will also make the work of gallium nitrate in following treatments in killing remaining HIV more efficient, since boluses of semen will have been removed by the douche.

EJACULATING HIV INFECTED SEMEN INTO AN ANUS OFTEN RESULTS IN HIV TRANSMISSION! This is why it is a state felony in 37 U.S. states for a person who knows he/she is HIV positive to have sex with another. Only about a quarter of infected MSM knew that their semen (and blood) were infected, thus the risk of spreading HIV from semen is extremely high. Perhaps some of these men knew they were HIV positive, but refused to say simply because they did not want to be seen as violating state laws. Receptive anal intercourse is the riskiest form of sex. In HIV infected men, even pre-cum -- the fluid before ejaculation -- contains HIV, so even if the inserter pulls out, infection is possible and likely. Men do get infected from both anal-receptive and anal-insertive sex, but anal-receptive sex is about 10 times more risky. HIV infected semen ejaculated into the anus/rectum carries a potential death sentence, strongly suggesting that gallium nitrate be used as an alternative treatment for HIV/AIDS. On the other hand, protected anal sex (condom, auto-sex, or toy use) carries a low to non-existent risk. In American male gay couples, only about 45% are monogamous, thus HIV transmission rates are high. The risk of transmitting HIV to a person that has razor burns or other skin irritation/injury on his/her bottom or genitals where infected semen can make contact with the broken tissue is moderately high to high.

SURVIVAL TIMES: With effective treatment, survival time after infection with HIV is roughly ten years, although after diagnosis of AIDS it is about one year. Although FDA approved drug treatments for AIDS and HIV can slow the course of the disease, there is currently no vaccine or cure. If there was a vaccine, then everyone taking it would become "HIV positive", without regard to whether or not they had HIV.

RISK FROM VARIOUS FORMS OF SEX:

The chart below gives relative risks for HIV transmission for various forms of sex.

High Risk for HIV Transmission

  • Receiving anal sex without using a condom

Medium Risk for HIV Transmission

  • Performing anal sex without a condom
  • Receiving anal sex without a condom in which the person performing the anal sex withdraws before ejaculation

Low Risk for HIV Transmission

  • Oral sex with an HIV positive person
  • Performing or receiving anal sex with a condom
  • Rimming
  • Fisting and fingering (when clean)

No Risk for HIV Transmission

  • Role playing and “dirty talk”
  • Massage
  • Kissing
  • Spanking, wrestling and bondage
  • Mutual masturbation
  • Frottage or “dry sex”
  • Use of clean anal toys such as dildos, butt-plugs, vibrators and beads

TRANSGENDER TRANSMISSION RISK: By race/ethnicity nationally, black/African American transgender women have the highest percentage of new HIV-positive test results. Higher percentages of newly identified HIV-positive test results were found among black/African American transgender women (56.3%) than among white (16.7%) or Latino (16.1%) transgender women. A review of studies of HIV infection in other countries with data available for transgender people estimated that HIV prevalence for transgender women was nearly 50 times as high as for other adults of reproductive age, whih is essentially identical to the risk of HIV in other MSM.

HETROSEXUAL COUPLES RISK: Researchers do not know with absolute certainty why the HIV epidemic has not spread to hetrosexual couples in the USA, but most suspect it is due to their high rates of monogamy. Some contrasting examples: In USA male gay couples, only about 45% are monogamous, and they have high rates of HIV/AIDS. African women are much less monogamous than American women, and they have much higher rates of infection than American women.

LESBIAN COUPLES RISK: According to this Center for Disease Control report, there are no reports of lesbian HIV infection, unless there were other transmission factors (drugs, shared needles etc.) involved! This strongly suggests that the only sexual means of transmitting HIV to another is by infected semen or anal mucus.

SEX LUBRICANTS: PRO-HIV OR ANTI-HIV? A recent medical research study of popular over-the-counter and mail-order water and glycerin based sex lubricants showed that the majority were found to be toxic to anal and rectum cells and tissue, apparently rendering MSM more vulnerable to infection of HIV and other sexually transmitted diseases. According to the article, two of the six lubricants, PRE and Wet Platinum, were shown to be safest for the cells, while Astroglide was the most toxic to anal and rectum cells and tissue. KY Jelly had the worst effect on rectal bacteria, essentially wiping out the entire colony. ID Glide and Elbow Grease had intermediate effects, the research team found. None of the lubricants was found to have measurable anti-HIV activity. Another study, showed that glycerin and the thickener polyquaternium-32, common ingredients in personal lubricants, had anti-HIV properties. A 2001 University of Texas study showed that three sex lubricants (Astroglide, Vagisil and ViAmor) are highly active against both HIV-infected leukocytes suspended in seminal fluid and active against cell-free HIV, under in vitro conditions that simulate in vivo conditions. A 2004 University of Texas study showed that Astroglide, KY Liquid, Replens, Vagisil, ViAmor, and Wet Stuff, each containing active ingredients identified as glycerin and polyquaternium-32 were anti-HIV in vitro. Those studies are countered by this 2011 study, which shows that Astroglide Liquid, Astroglide Warming Liquid, Astroglide Glycerin & Paraben-Free Liquid, and Astroglide Silken Secret, significantly enhanced HIV-1 replication (p<0.0001). This 2012 report suggested that some lubricant products may increase vulnerability to STIs, including HIV. Consequently, researchers have worked on reformulating a vaginal sex lubricant to be safe for anal sex. A reduced glycerin anti-HIV product for both vagina and rectum use - Tenofovir Vaginal Gel - appears effective in protecting cells against HIV and does not damage rectal cells according to this article.

Due to the serious probems associated with some water/glycerin sex lubricants when used anally, it seems to me that only silicone-based lubricants should be used.

The gay barebacker's favorite, Crisco, other oils and greases such as Vicks and Mentholatum must not be used with condoms as they de-grade the rubber and cause failure of condoms. Bottoms find that Vicks and Mentholatum (due to their menthol content) introduced into the anus produce a surprisingly cool feeling in the anus that they greatly enjoy. They have no similar effect on the penis.

ANAL MUCUS: The rectum excretes a very slippery, transparent, jelly-like fluid called anal mucus. Anal mucus is another bodily fluid that can transmit the HIV virus if the bottom is HIV positive. In fact, anal mucus can carry more HIV than semen or blood from the same subject – by about 500% in the case of blood, and 2500% in the case of semen. Anal mucus must come in contact with a mucus membrane or damaged tissue for transmission to occur. This can occur through the penis foreskin and surrounding areas, the eye of the penis to the urethra (also a mucous membrane), or through tiny (often invisible) breaks in the skin of the penis when in contact with HIV-infected anal mucus. Anal mucus can also carry blood from the anus/rectum indicating internal damage, suggesting greater risk of HIV transmission to the bottom. Having adequate gallium nitrate in the blood to kill HIV seems imperative as an alternative treatment for HIV/AIDS.

INJURIES: Pain and bleeding often results from tearing or other injuries, and one can clearly see that the potential for injury in anal sex is high, helping to explain the reason for the high rate of transmission of HIV in anal sex. Treatment of the anal/rectal tract with 1% gallium nitrate, in a manner identical for preventing HIV infection, will usually immediately stop internal bleeding and be quite healing. Higher concentrations inside the anus/rectum will cause pain. See your physician if you experience protracted internal pain, especially if there is continued severe bleeding, since there may be a rupture or tear in the rectum which might require surgery. Also, get tested for HIV. You might try the at home test called Oraquick, which has been used by health care professionals for many years. Here is what the FDA says about that test. Also, see discussion at bottom of this page about stopping anal bleeding with 1% gallium nitrate solutions.

OUR GOAL: PREVENT INFECTION!

A CASE REPORT OF GALLIUM NITRATE FOR HIV: A male HIV positive client who was treating his arthritis with gallium nitrate, told me in February of 2009 that before taking gallium that his CD4+ T-cell count was very low at < 200 cells/mm3. After taking gallium nitrate his CD4+ T-cell lymphocyte count rose to 2200, more than an 11-fold increase. This is consistent with the finding of Stapleton that Ga(III) prevented T-cell death.

His report is extremely important since it shows, for the first time, that gallium nitrate can increase peripheral blood CD4+ cells and have an undeniably beneficial effect on HIV/AIDS, although there was no discussion of intestinal CD4+ cell changes or viral titer. Consequently, I believe that it is imperative for there to be enough gallium nitrate in the blood to be an effective alternative treatment for HIV/AIDS. Had he not commented to me about this, nearly as a matter of fact, I would not have written this page. This non-judgmental essay, for the first time, explores the potential for gallium nitrate (a potent anti-HIV agent) to prevent HIV infection by applying it to the penis, anus, vagina and mouth at the time of the sex act.

GALLIUM NITRATE SAFETY: Is gallium nitrate safe for use in trying to prevent HIV/AIDS? I think so. People have been using low doses to treat arthritis and a number of other conditions for many years, and I have not heard of any safety related complaints. See my article on treating arthritis with gallium nitrate here. I have used it frequently to treat my own old-man aches and pains. I think that the risk of too much gallium in the blood is similar to getting too much of any mineral, since they can displace each other. Perhaps one should take dietary supplements of calcium, iron and magnesium to compensate.

The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which inhibit the replication of essentially 100% of HIV. Here is a 2010 review of medical uses of gallium and toxicities. What is not known is how long gallium needs to be in contact with HIV for it to inhibit replication.

Most importantly, gallium nitrate should never be used with drugs that are known to harm the kidneys (e.g., gentamicin and amphotericin B) because of the increased risk for severe kidney problems. Overdose symptoms may include nausea and vomiting, or urinating less than usual. Thorough hydration (lots and lots and lots of drinking water) is a good antidote to gallium overdose. That is one reason we always mix it in lots of water.

CONCENTRATED GALLIUM NITRATE: The 42% gallium nitrate solutions that we market contain 57,000-milligrams of elemental gallium per each half-liter bottle. The product is sufficiently concentrated that it feels "oily" and is quite slippery on the skin. This feeling of oiliness on the skin must not be confused with any sex lubricant value, because it is not there. The pH of the 42% gallium nitrate product is 1 (highly acidic), even though it is highly buffered by gallium (III). Since the pH is so low, it would be highly injurious to delicate anal/rectum or vagina/cervix tissues, and it causes extreme pain inside the rectum. Diluting 42% gallium nitrate solutions to 1% solutions raises pH to 3.5. Gallium nitrate solutions can be stored in any glass or plastic (non metallic) container and the solutions should be kept sealed to protect against evaporation. The 1% gallium nitrate solutions do not cause pain or appear to be harmful to the mouth, penis, anus/rectum or vagina/cervix, however it has not been formally tested in clinical trials or any other formal setting.

HOW TO MAKE ONE PERCENT GALLIUM NITRATE SOLUTIONS:

  • Obtain 42% gallium nitrate solutions here. (It is marketed only for equine use.) The product's daily cost for a person is about a dollar per day.
  • To make a 1% gallium nitrate solution, add 12-ML of the 42% gallium nitrate solution to 500-ML (a pint) of distilled water.
  • This creates a working stock or a supply for later use in much smaller volumes as described below.

ORAL USE: For oral use (including swallowing) gallium nitrate solutions must not be stronger than a 1% aqueous solution (volume basis). The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. The daily human dose of the 1% solution would usually be 50 to 150 CC of the 1% solution, depending on one's weight. For example, a 120 pound person would take 50CC of the 1% solution daily, while a 240 pound person would take 100CC of the solution. The exact formula for a person's daily dosage is: the person's weight in pounds multiplied by 0.42 CC. This solution will make the mouth feel dry. I suggest that this dosage be taken orally daily in an effort to keep blood levels of gallium nitrate high enough to prevent HIV replication. Do not regularly exceed consuming 100 CC of the 1% gallium nitrate solution per day. Remember that the gallium must contact the virus and that boluses of semen in the mouth need to be broken up (by rapid mouth swishing and/or spitting it out) while the gallium nitrate is in the mouth. That will help assure full contact with the virus and their demise. The 1% solution has been used orally in many thousands of people (mainly in treating arthritis). Stronger solutions can cause increasingly severe oral pain. After oral sex, wash the mouth with the 1% gallium nitrate solutions for about 15 minutes, and slowly swallow it as a semen chaser in an effort to directly inhibit replication of HIV in the swallowed semen.

TOPICAL GALLIUM NITRATE WASHES: Topical anti-HIV "after sex" washes for the penis, vagina/cervix and anus/rectum can be prepared in the same manner as for oral use. The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV and should be an effective alternative treatment for HIV/AIDS. Intra-anal doses of the 1% gallium nitrate solutions are usually in the 50 to 100 CC range, with repititions being required due to leakage.

Used topically in the anus (and vagina), the anti-HIV gallium nitrate solutions will be used and absorbed exactly where it is needed to try to prevent HIV infection from infected semen. Washing the penis is straight forward, while washing the vagina/cervix and anus/rectum would respectively require douching and anal syringes. An anal syringe can deliver gallium nitrate solutions past the anal sphincter and into the rectum whre it can exert its benefits as an alternative treatment for HIV/AIDS.

Due to the extreme risk of HIV infection originating in the gastrointestinal tract (60-times any other means) from infected semen, anally introduced 1% gallium nitrate solutions should be left in the rectum. Oral 1% solutions should be taken daily for several days prior to anal sex to help insure a useful alternative treatment for HIV/AIDS. Every effort must be made to keep the solutions in the anus/rectum or to replace it if it leaks out the anus. Perhaps the best time to treat the anus/rectum with the 1% solutions (immediately after sex) would immediately afer sex at bedtime or other times when the person will be recumbent. An anus-up position would be helpful to retain the solution in the event of anal dilation or prolapse. Remaining recumbent for hours helps prevent leakage. What has been said here generally applies to the vagina/cervix also, although the risk of transmission is sufficiently reduced that simple rinsing and keeping the vagina wet with the 1% gallium nitrate solutions for about one hour should suffice.

An anal syringe will deliver the proper amount of the 1% solution of gallium nitrate. Don't overdose, but perhaps a second and even a third application during or after anal sex would be well advised, especially if there is anal leakage.

Remember that my main point in using gallium nitrate is to try to prevent HIV infection at the source (anus, rectum, mouth, vagina), since it seems best to remain free of HIV infection so that it does not need to be treated later. Remember that HIV infection is permanent!

Gallium nitrate - in the concentrations used here - is also bacteriostatic to all iron dependent bacteria, which excludes the beneficial gastrointestinal bacteria, since none of which are iron-dependant. People carry about 100 trillion microorganisms in our intestines, a number ten times greater than the total number of cells in our bodies. Had gallium been harmful to intestinal bacteria in horses, they would have become colicy, but none have ever had an intestinal issue from gallium nitrate. Neither have people using gallium nitrate for arthritis or other illnesses such as arthritis, Lymes or Chron's diseases. About 80% of all pathogenic (harmful) bacteria and fungi are killed by gallium nitrate solutions. Actually, gallium can be more accurately thought of as a "birth control" agent for iron-dependent bacteria and fungi, and they die-off naturally - not from gallium toxicity. Consequently, they never become resistant to gallium. The bacteria and fungi see gallium as if it were iron, and they use it as if it were iron. Unfortunately for the bacteria and fungi, gallium (III) will not become gallium (II), while iron (III) will become iron (II), and the bacteria cannot replicate. Look at the list of iron dependent bacteria above, since some of them are found in female urinary tract infections.

alternative treatment for HIV/AIDS - gallium nitrateTHE EASY WAY OUT: Why bother making an anti-HIV anal wash when condoms would do the same thing, that being prevent transmission of HIV?

    CONDOMS ARE VASTLY, VASTLY PREFERED!
But, gays have rejected condoms for the most part. Why? Rejection of condoms in the MSM community resulted from the MSM attitude towards HIV/AIDS of, "Oh! What the hell, there are medicines that take care of HIV/AIDS." If anyone is interested, twenty-four hour tests of Trojan® non-lubricated rubber condoms show that gallium nitrate solutions do not harm them. I will let others promote celibacy and condoms. However, I will mention that the statistical odds of being exposed to HIV through unprotected anal MSM sex is the same as being shot while playing Russian roulette with a revolver. Remember, the Grim Reaper rides bareback.

COMPLICATIONS AND SIDE EFFECTS OF HAART DRUGS: Have you thought about the complications and side effects from HAART drug treatment for AIDS? Did you know that about 25% of HIV patients stop therapy within the first year on HAART drugs because of side effects? What happens to them? I suspect they have a miserable death. Would you really enjoy the following complications and side effects for the rest of your life? Some common side effects of HAART medicines include nausea, vomiting, diarrhea, liver failure, skin rashes, swelling of the face, lips and tongue, kidney stones, anemia, peripheral neuropathy (chronic pain), pancreatitis, myelosuppression (decreased bone marrow production of red blood cells, white blood cells and platelets), increased cholesterol and triglycerides, cardiovascular disease, rapid aging, suicide, diabetes, depression, dizziness, abdominal pain, insomnia and ugly "fat pads". Did you know that up to 75% of all HIV/AIDS patients develop vision problems, with about 20% becoming totally blind? Here is a 1996 medical journal article that lists side effects of some of the HIV drugs. There are too many to list here. Read the article NOW! Educate yourself about side effects. Look through this Google search for "HIV medicine" and "side effects", and this Google search for "HAART" and "side effects". HIV/AIDS is a major, major jackpot for physicians and hospitals.

What about the new "preventive" drug for HIV, Truvada? Look at the side effects listed on their site, and ask yourself if using condoms and gallium nitrate is a better idea. The list is long, but includes thinning of bones, nausea, vomiting, muscle pain, and/or weakness, kidney problems, diarrhea, dizziness, nausea, headache, fatigue, abnormal dreams, sleeping problems, rash, depression, vomiting, inflammation of the pancreas and liver, allergic reaction, shortness of breath, pain, fatty liver, stomach pain, weakness, indigestion, and intestinal gas and other deleterious effects.

alternative treatment for HIV/AIDS - gallium nitrateCAVEATS, CONCERNS, WARNINGS and MISCELLANEOUS THOUGHTS: Although there is no doubt that 1% gallium nitrate (or stronger) is anti-HIV, the wise person would use a condom for all anal sex. They are as near 100% fool proof as anything. Ideally, they would be used with gallium nitrate solutions. Although gallium nitrate may be useful in preventing (or treating) HIV infection by stopping the replication of the viruses, thus potentially preventing AIDS when used both orally and intra-anally, there is no guarantee that 100% of the HIV viruses will be killed by Gallium since it must directly contact the virus. I am certain that results will vary, depending upon the skills and habits developed.

Please remember that this essay tries to suggest a new way to PREVENT HIV infection, not treat it, and to provide an alternative treatment for HIV/AIDS. It is my contention that it is best to try to "PREVENT" it with topical washes, especially of the colon, since it is over 60-times more likely to become fatally infected with HIV than any other tissue. See the Stapleton patent for details on "treating" HIV with gallium nitrate. All in all, it seems to me that anal sex is extremely risky business. Clearly, HIV infection can terminate the health, wealth and lives of many otherwise innocent and healthy people. It really makes money for doctors and hospitals. Do we want that? I say NO!

TREATMENT OF EXISTING HIV INFECTION AND AIDS: Although this essay is primarily about preventing infection through topical use of gallium nitrate, treatment of HIV/AIDS remains a very important issue. Remember from above that a male HIV positive client who was treating arthritis with gallium nitrate, told me that before taking gallium his CD4+ T-cell count was very low at < 200 cells/mm3). After taking gallium nitrate his CD4+ T-cell lymphocyte count rose to 2200, more than an 11-fold increase. Treating HIV orally apparently killed his HIV, allowing the T-cells to return to a normal level. This is the main goal of HIV treatment, to kill the virus and increase the T-cell counts back to normal so that the immune system function is restored, thus preventing or curing AIDS. What would be the dosage of oral gallium nirate solutions? I suggest the same as the doses that are suggested to prevent HIV in oral sex, which is about 100 CC of the 1% solution daily. The 1% gallium nitrate solutions are 345-micromol ionic Gallium solutions, which kills essentially 100% of HIV. If gallium nitrate is stopped, will the HIV return? That is unknown.

Concerning the possibility of criticism of this extremely early and essentially uncontrolled research, I quote Albert Einstein who said, "If we knew what it was we were doing, it would not be called research, would it?"

Consequently, I would appreciate anecdotes/case histories (diagnosis, previous treatment, results of previous treatment, effects from gallium, records of results, especially CD-4 counts, side effects, various records of opportunistic infections related to HIV) for publication as a testimonial below. I will also publish constructive comments and questions. Your e-mail address on the testimonial would add credibility. Confidential email addresses are available through Hotmail, Gmail and others. If gallium does work as expected, I will write up the collected results (protecting confidentiality) for submission to a medical journal. Not that they would publish it! Heaven forbid! A cheap and effective nutrient preventative for HIV and AIDS? The pharmaceutical companies would have me shot!

ON YOUR MARK, GET SET, GO! I will publish below the exact words (testimonials) of anyone that tries gallium nitrate as a preventative for HIV and/or AIDS. I am most interested in experiences using the anal route, since that has the potential to stop HIV infection in its tracks in the most people. Are there sex lubricants that work well with gallium nitrate? Have you tried Mentholatum or Vicks as sex lubricants? They should be wonderfully titillating and erotic. Although prevention is very important to the gay man and gallium nitrate can be used now, only carefully controlled, large scale clinical studies would be convincing to the medical profession.

CASE NOT CLOSED:

  • Did you know that not everyone agrees that HIV causes AIDS?
  • Did you know that the evidence is completely missing?
  • Did you know that Nobel Prize winner Kary Mullis thinks that the whole thing is a scam? Read Chapter 18,"Case Not Closed", from his book "Dancing Naked in the Mind field" here, wherein he debunks the entire notion of HIV causing AIDS.
  • Did you know that many of the old "War on Cancer" researchers just needed something else to work on? So they invented the notion that one of the retroviruses, HIV, caused AIDS.

DIETARY SUPPLEMENTS: HELP YOU OR KILL YOU?

No one knows more about nutrition and the immune system than the highly regarded RK Chandra in Canada. The following is from one of his abstracts: "Deficiency of certain micronutrients results in altered immune response: this is observed even when the deficiency state is relatively mild. Of the micronutrients, zinc, selenium, iron, copper, vitamins A, C, E and B6, and folic acid have important influences on T-cell immune responses. In this 1999 article Chandra reported that zinc deficiency is associated with profound impairment of T-cell-mediated immunity such as lymphocyte stimulation response, decreased CD4+:CD8+ cells, and decreased chemotaxis of phagocytes. In addition, the level of thymulin, which is a Zn-dependent hormone, is markedly decreased.

Wouldn't supplementation with these nutrients, especially zinc, be advised in improving the T-cell immune system? One would certainly think so, but supplementing zinc and some other nutrients can either shorten the lives of HIV/AIDS patients or extend it according to several studies. Are they an effective alternative treatment for HIV/AIDS? For example:

  • Tang et al in 1993 showed in this study that the highest levels of total intake (from food and supplements) of vitamins C and B1 and niacin were associated with a significantly decreased progression rate to AIDS. The relation between total vitamin A intake and progression to AIDS appeared to be U-shaped; the lowest and highest quartiles of intake did most poorly, while the middle two quartiles were associated with significantly slower progression to AIDS. Increased intake of zinc was significantly associated with an increased risk of progression to AIDS.
  • In 1996, Tang et al. showed that increased intake of the B-group vitamins was independently associated with improved survival. Any intake of zinc supplements, however, was associated with poorer survival.
  • A 1997 report by Baum et al. showed that selenium deficiency is an independent predictor of impaired survival for those with HIV-1 infection. When all factors that could affect survival, including CD4 counts <200/mm3 at baseline, CD4 levels over time, and nutrient deficiencies were considered jointly, only CD4 counts over time and selenium deficiency in this study were significantly associated with mortality.
  • In 2007, Hurwitz showed that daily selenium supplementation of 200 micrograms per day can slow the progression of HIV-1 viral burden and provide indirect improvement of CD4 count.
  • In 2010, Baum et al. showed that zinc supplementation (12 mg of elemental zinc for women and 15 mg for men) reduced 4-fold the likelihood of immunological failure. Viral load was not affected by zinc supplementation. Zinc supplementation also reduced the rate of diarrhea by more than half. There was no significant difference in mortality between the the zinc treated and placebo groups. This study demonstrated that long-term (18-month) zinc supplementation at nutritional levels delayed immunological failure and decreased diarrhea over time. This evidence supports the use of zinc supplementation as an adjunct therapy for HIV-infected adult cohorts with poor viral control.
  • In 2013 Baum et al. showed that supplementation of multivitamins (B vitamins and vitamins C and E) and selenium was safe and significantly reduced the risk of immune decline and morbidity in HIV positive patients when started in the early stage of disease, although supplementation had no effect on viral load.

Should one take selenium? I think so, especially since it doen't seem to hurt and it is the second most called for nutrient for the T-cell system according to Chandra.

How do we respond to the conflicting evidence between the negative Tang reports and the 2010 Baum report concerning the effects of zinc? How can the finding that zinc can either hurt or help be true? I think it gets back to what Kerry Mullis claims, that being that HIV does not directly cause AIDS. Rather, HIV consumes so much zinc from the blood that the T-cell immune system and the rest of the body are starved for zinc. Clearly, HIV, like most organisms, requires zinc for replication. High or very low zinc concentrations interfere with replication. When there is inadequate zinc, the T-cell system becomes greatly impaired, just like Chandra reported, and AIDS develops. This gives rise to my hypothesis that there may be no difference between HIV-induced AIDS and zinc deficiency induced AIDS. Does one supplement with zinc? Yes or no? Keep up with the zinc and HIV/AIDS story here.

SUM IT UP IN A NUTSHELL GEORGE! To make anal sex safer, the rectum should be clean before and after anal sex. Condoms are absolutely vital. Slowly dialate the anus. If pain results, stop! Use 1% gallium nitrate oral solutions daily and topically after anal sex in an effort to kill HIV.

You are on your own, best wishes.

George Eby
George Eby Research Institute
Austin, Texas
Telephone 1-512-263-0805
george.eby@george-eby-research.com

I dedicate this essay to my son, Colin Martin Eby, who was gay and died at age 32 on May 14, 2011.



TESTIMONIALS

Hi George,

I have been using 50CC of a 1% gallium nitrate solution made from your 42% gallium nitrate product (that I found on the internet) after each MSM encounter for over a year. I use it on myself and my partners. Recently, I had bareback sex with a man with a really big, very hard cock and he hurt me (far too rough/brutal). I made him stop and I nursed my little anus with Mentholatum Ointment (feels really good). For some reason, I did not use gallium nitrate, perhaps because he had not ejaculated in me. Immediately after that, I noticed anal bleeding every time I checked my anus with my finger, and blood on toilet paper every time I wiped. This went on for about a week. I am on Warfarin (Coumadin), so my blood is quite thin. I avoided sex for over a week, nursing my bleeding anus. One day, I met a man that I thought was perfect and we had a deep and meaningful (bloody) bareback sexual relation. He fucked my anus until I thought I was going to pass out! Neither of us cared about the blood, and it actually seemed to stimulate us even more. Immediately after that, I used the 1% gallium nitrate solution (50 CC) intra-anally as a precaution against HIV. That was at bedtime, and I slept like a baby. I did awaken once to pee, and I decided to wipe my ass to see what I could see. I noticed a bit of blackish-red blood. In the morning I went to poop, expecting more blood, but I noticed no blood at all! I was thrilled! Even after a week and some really good loving, no more anal bleeding. I used gallium each time. George, is it possible that gallium nitrate stops bleeding? If so, I will have two very good reasons to always use 1% gallium nitrate after anal sex. No, that's not right, I will have three or four good reasons if I include anti-bacterial and anti-fungal effects of gallium nitrate. There is no telling what microbial junk these pretty-boys introduce into my anus! Thank you!!! BTW, my T-cell count remains normal, and my whole immune system seems normal too, with no evidence of HIV according to multiple blood tests.

Thanks, Billy B.


Hi Billy,

You were right to avoid sex while bleeding, it would be a perfect way to transmit a disease, especially HIV, from another to you, even though your own feces is very unlikely to do so according to a proctologist I know. Also, remember that gallium ion (like found with gallium nitrate) is bacteriostatic to nearly all pathogens. I had not heard of an anti-bleeding effect of gallium before, so I checked the medical literature. There is a 2011 medical journal article that describes the ability of gallium nitrate (my 14% solution) to stop bleeding rapidly compared with controls. It did not refer to anal bleeding, butt... See the article here. I remember one of those scientists since he bought the gallium nitrate from me. Interestingly, it worked on both Warfarin and non-Warfarin treated subjects. They noticed a blackish-red (brown) clot too from use of gallium. They used 14% solution topically, but a 14% solution intra-anally would cause significant anal pain. Please remember that their report is the only published information on the matter. I am impressed and pleased that your use of a 1% solution was effective. I don't see any risk from using 50 CC of 1% gallium nitrate solution(s) to stop anal bleeding, especially since the 1% solutions intra-anally are in general use to try to prevent HIV transmission. Also, remember that gallium is highly bacteriostatic to iron dependant bacteria (this excludes intestinal bacteria because they are not iron dependant); so all in all, it appears good for the anus and rectum.

Incidentally, a man recently reported that he used 14% gallium nitrate to stop bleeding on a penis that had started to bleed shortly after a circumsision. He reported that the gallium nitrate made a large and very hard "blood clot" on each suture causing local pain over the following several weeks as the circumcision healed. Apparently gallium nitrate should not be used on "sutures".

NOTES: By early summer of 2015, I have now had numerous men tell me that they had HIV/AIDS with very low T-cell counts and that after regular use of intra-anal and oral gallium nitrate, their T-cell counts had normalized (increased 10 to 12-fold) and they felt much better. I have no knowledge of changes in their intestinal T-cell counts, but anal gallium has a real chance of working. Unfortunately, I have no further data or ability to confirm their comments.